Tumor necrosis factor alpha inhibitors for the treatment of dermatologic diseases

Hidradenitis suppurativa Research

Author(s): Trent JT, Kerdel FA

Tumor necrosis factor alpha (TNFalpha) is involved in cell differentiation, mitogenesis, cytotoxic responses, inflammation, immunomodulation, and wound healing. Because of its numerous roles, it was thought that inhibition of TNF may aid in the treatment of certain dermatologic diseases such as psoriasis, hidradentitis suppurativa, pyoderma gangrenosum, Behcet ‘s syndrome, and graft versus host disease. The efficacy of these agents has proven impressive and short-term side effects have been few and relatively benign.

Dermatology Journal and/or Publisher

Journal Name: Dermatology nursing
Journal Abbreviation: Dermatol Nurs
Journal Date Published: 2005-05-26

National Center for Biotechnology Information

PMID: 15916184
Article Source: http://www.ncbi.nlm.nih.gov/pubmed/15916184
Lasted Revision: 2016-10-21

Abstract Source: National Center for Biotechnology Information, U.S. National Library of Medicine Abstract Query for Hidradenitis suppurativa (HS).


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