Treatment of severe recalcitrant hidradenitis suppurativa with adalimumab

Hidradenitis suppurativa Research


Author(s): Harde V, Mrowietz U

Hidradenitis suppurativa is a chronic inflammatory skin disease featuring inflammatory nodules, fistulas and discharge of secretions in the intertriginous regions. Without therapy the disease is chronic and progressive. The most effective treatment is the radical wide excision of the affected areas. Systemic antibiotics, immunosuppressants, oral retinoids or antiandrogens have limited beneficial effects. TNF-alpha antagonists may represent a new therapeutic approach for patients suffering from severe hidradenitis suppurativa offering promising positive influence on the disease outcome. In contrast to infliximab and etanercept, there are only few reports describing the use of adalimumab in severe hidradenitis suppurativa. Here we report a case of a patient with severe recalcitrant hidradenitis suppurativa successfully treated with adalimumab.


Dermatology Journal and/or Publisher

Journal Name: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
Journal Abbreviation: J Dtsch Dermatol Ges
Journal Date Published: 2009-04-17


National Center for Biotechnology Information

PMID: 19371236
Article Source: http://www.ncbi.nlm.nih.gov/pubmed/19371236
Lasted Revision: 2015-11-19


Abstract Source: National Center for Biotechnology Information, U.S. National Library of Medicine Abstract Query for Hidradenitis suppurativa (HS).


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