Title: Opioid, Alcohol, and Cannabis Misuse Among Patients with Hidradenitis Suppurativa: a population-based analysis in the United States

Hidradenitis suppurativa Research


Author(s): Garg A, Papagermanos V, Midura M, Strunk A, Merson J

BACKGROUND: Patients with hidradenitis suppurativa (HS) experience chronic pain and have significant physical, emotional and psychological disease impact. These patients may be at risk for substance abuse.

OBJECTIVE: To evaluate substance use disorder (SUD) among HS patients in the United States.

METHODS: Cross-sectional analysis of adult HS patients (n = 32,625) identified using electronic health records data from a population-based sample of over 50 million patients.

RESULTS: The prevalence of SUD among patients with HS was 4.0% (1,315/32,625), compared to 2.0% (195,260/9,581,640) for patients without HS (p<0.001). The most common forms of substance misuse among HS patients were alcohol (630/1,315; 47.9% of SUD cases), followed by opioids (430/1,315, 32.7% of SUD cases) and cannabis (430/1,315, 29.7% of SUD cases). HS patients had 1.50 [95% CI 1.42-1.59] times the adjusted odds of SUD compared to patients without HS. HS patients had significantly greater odds of SUD across demographic subgroups. The association between HS and SUD was generally stronger for patients aged 45-64 years, non-whites, privately-insured, and those without depressive or anxiety disorder.

LIMITATIONS: SUD may not be accurately diagnosed.

CONCLUSION: Patients with HS have higher odds of SUD and may benefit from periodic screening for substance abuse.


Dermatology Journal and/or Publisher

Journal Name: Journal of the American Academy of Dermatology
Journal Abbreviation: J. Am. Acad. Dermatol.
Journal Date Published:


National Center for Biotechnology Information

PMID: 29499293
Article Source: http://www.ncbi.nlm.nih.gov/pubmed/29499293
Lasted Revision: 2018-03-02


Abstract Source: National Center for Biotechnology Information, U.S. National Library of Medicine Abstract Query for Hidradenitis suppurativa (HS).


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