Author(s): Cooper SM, Dawber RP, Hilton-Jones D
Three cases of androgen-dependent disease in females with myotonic dystrophy are described. Serum androgens in individuals affected by myotonic dystrophy are known to be lower on average than in normal controls. Despite this these three females developed diseases that are androgen dependent, including acne, hidradenitis suppurativa, androgenetic alopecia and keratosis pilaris. These cases support the hypothesis that the peripheral response to androgens rather than absolute circulating levels of androgens is important in androgen-dependent conditions.
Dermatology Journal and/or Publisher
Journal Name: Journal of the European Academy of Dermatology and Venereology : JEADV
Journal Abbreviation: J Eur Acad Dermatol Venereol
Journal Date Published: 2003-02-26
National Center for Biotechnology Information
Article Source: http://www.ncbi.nlm.nih.gov/pubmed/12602971
Lasted Revision: 2004-11-17
Abstract Source: National Center for Biotechnology Information, U.S. National Library of Medicine Abstract Query for Hidradenitis suppurativa (HS).