Author(s): Vargas Pérez M, Sevilla Pérez B
The acronym of SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis and osteitis) combines a cluster of cutaneous and musculoskeletal manifestations, such as hyperostosis of bones of the anterior chest wall associated with acne fulminans and hidradenitis suppurativa. There are no validated diagnostic criteria in children. Nonsteroidal anti-inflammatory drugs are not always sufficient, and the use of corticosteroids, disease-modifying agents, tumor necrosis factor-α inhibitors or bisphosphonates may be necessary. We present the case of a child with polyarticular involvement, osteoarthritis of the sternoclavicular joint with severe inflammatory disorders and acne conglobata, with an excellent response to intravenous pamidronate.
Dermatology Journal and/or Publisher
Journal Name: Reumatologia clinica
Journal Abbreviation: Reumatol Clin
Journal Date Published: 2016-12-20
National Center for Biotechnology Information
Article Source: http://www.ncbi.nlm.nih.gov/pubmed/27993538
Lasted Revision: 2016-12-21
Abstract Source: National Center for Biotechnology Information, U.S. National Library of Medicine Abstract Query for Hidradenitis suppurativa (HS).