PSTPIP1 Gene mutation in a pyoderma gangrenosum, acne and suppurative hidradenitis (PASH) Syndrome


Journal: Br. J. Dermatol. 2015 Dec;

Author(s): Calderón-Castrat X, Bancalari-Diaz D, Román-Curto C, Romo-Melgar A, Amorós-Cerdán D, A Alcaraz-Mas L, Fernández-López E, Cañueto J

Pyoderma gangrenosum (PG) acne and suppurative hidradenitis (SH) (PASH) syndrome is a recently described condition which belongs to the spectrum of autoinflammatory diseases (AIDs). (1) AIDs are a group of heterozygous disorders characterized by disregulation of the innate immune response. (2) PSTPIP1 gene mutations affecting proteins of the inflammasome complex or proteins that regulate it’s function, responsible for the inflammatory pathway, are associated with AIDs. This article is protected by copyright. All rights reserved.

Dermatology Journal and/or Publisher

Journal Name: The British journal of dermatology
Journal Abbreviation: Br. J. Dermatol.
Journal Volume: , Issue:
Journal Date Published: 2015-12-29

National Center for Biotechnology Information

PMI ID: 26713508
Created: 2015-12-29

Abstract Source: National Center for Biotechnology Information, U.S. National Library of Medicine Abstract Query for “Hidradenitis suppurativa”


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