Potential role of FoxO1 and mTORC1 in the pathogenesis of Western diet-induced acne

Pubmed Article

National Center for Biotechnology Information, U.S. National Library of Medicine

Acne in adolescents of developed countries is an epidemic skin disease and has currently been linked to the Western diet (WD). It is the intention of this viewpoint to discuss the possible impact of WD-mediated nutrient signalling in the pathogenesis of acne. High glycaemic load and dairy protein consumption both increase insulin/insulin-like growth factor-1 (IGF-1) signalling (IIS) that is superimposed on elevated IGF-1 signalling of puberty. The cell’s nutritional status is primarily sensed by the forkhea

Source: Potential role of FoxO1 and mTORC1 in the pathogenesis of Western diet-induced acne. – PubMed – NCBI

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