222 Completed suicide in patients with Hidradenitis suppurativa (HS): A population analysis in the United States
Hidradenitis suppurativa (HS) is known to have substantial impact on quality of life and patients may be at greater risk for suicide as a result. We evaluated suicide risk among patients with HS in the United States, using a population-based data. The study included patients aged 18 years or older with an active status from 2011 to 2016 in electronic health records of 27 participating health care organizations across all US census regions representing a demographically heterogenous population.
The Systemized Nomenclature of Medicine – Clinical Terms (SNOMED-CT) of ‘hidradenitis’ and ‘suicide’ were used to identify HS patients and patients with comlete suicide, respectively. Mutlivariable logistic regression models were used to adjust odds ratios for age, gender, and race. 49,380 HS patients were compared to the control of approximately 23 million patients without HS.The absolute risk of completed suicide in the HS and control populations was 0.8% (415/49,380), and 0.3% (67,920/ 23,153,180), respectively.
Compared to those without HS, patients with HS had increased odds of suicide (crude ratio [OR 2.88, 95% CI 2.62-3.18], adjusted for age, gender, and race [OR 2.43, 95% CI 2.21-2.68]). The effect of HS on suicide risk increased with advancing age-group, and the greatest effect of HS on suicide risk occurred among patients aged 60 years or older [OR 3.62, 95% CI 2.34-5.62].
Patients with HS have a greater than two-fold risk of completed suicide.
Patients with HS may require an interdisciplinary approach to risk assessment and prevention of suicide.Suicide