[Lupus erythematosus discoid-like dermatosis in a carrier of septic granulomatosis]

Hidradenitis suppurativa Research

Author(s): Hafner J, Panizzon R, Bruckner-Tuderman L, Wüthrich B, Seger RA, Burg G

We present a clinically atypical case of discoid lupus erythematosus in the mother of a boy with chronic granulomatous disease. In this disorder, the phagocytes are unable to produce superoxide anion to degrade incorporated microorganisms. In addition to a discoid lupus erythematosus-like skin disease, recurrent stomatitis aphthosa, hidradenitis suppurativa and Raynaud phenomenon are markedly associated with heterozygote carriers of chronic granulomatous disease. Based on this conspicuous association, diverse models concerning the pathogenesis of lupus erythematosus are discussed.

Dermatology Journal and/or Publisher

Journal Name: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete
Journal Abbreviation: Hautarzt
Journal Date Published: 1993-10-04

National Center for Biotechnology Information

PMID: 8365880
Article Source: http://www.ncbi.nlm.nih.gov/pubmed/8365880
Lasted Revision: 2017-11-16

Abstract Source: National Center for Biotechnology Information, U.S. National Library of Medicine Abstract Query for Hidradenitis suppurativa (HS).


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