Long-term results of isotretinoin in the treatment of 68 patients with hidradenitis suppurativa

Hidradenitis suppurativa Research

Author(s): Boer J, van Gemert MJ

BACKGROUND: Oral isotretinoin has been used to treat mild to severe hidradenitis suppurativa (HS).

OBJECTIVE: We reviewed the results of low-dose isotretinoin for 4 to 6 months in the treatment of 68 patients with HS.

METHODS: This is a retrospective study. Data are presented in terms of response rate, long-term follow-up, and the relation between response rate and severity.

RESULTS: In 16 patients (23.5%), the condition completely cleared during initial therapy and 11 patients (16.2%) maintained their improvement during the follow-up period. Treatment was more successful in the milder forms of HS.

CONCLUSION: Monotherapy with isotretinoin for patients with HS usually has a limited therapeutic effect.

Dermatology Journal and/or Publisher

Journal Name: Journal of the American Academy of Dermatology
Journal Abbreviation: J. Am. Acad. Dermatol.
Journal Date Published: 1999-02-18

National Center for Biotechnology Information

PMID: 9922015
Article Source: http://www.ncbi.nlm.nih.gov/pubmed/9922015
Lasted Revision: 2013-11-21

Abstract Source: National Center for Biotechnology Information, U.S. National Library of Medicine Abstract Query for Hidradenitis suppurativa (HS).


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