Hidradenitis Suppurativa, Metabolic Syndrome, and Demodex spp. infestation

Hidradenitis suppurativa Research


Author(s): Ünal E, Güvendi Akçınar U, Arduç A

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease. This type of dermatosis with underlying chronic inflammation significantly affects the quality of life and may be accompanied by many comorbidities. In this case, Demodex spp. was associated with treatment-resistant and persistent course of skin diseases. A 46-year-old female patient applied to our clinic with complaints of lesions on the body and hip. Her dermatological examination revealed abscess formation and post-inflammatory pigmentation. Millimetric scar formation and improved folliculitis-like lesions were observed on both glutei. These complaints started 7 years ago and become more intense and severe by time. Owing to the diagnoses of diabetes mellitus, hypertension, and hyperlipidemia, the patient was monitored for metabolic syndrome. In the cultures taken from the lesions, no growth was seen. A standardized skin surface biopsy of the patient demonstrated demodicosis. The patient was treated with oral metronidazole and topical permethrin lotion, whereupon a pronounced recovery was observed in her clinical condition. In the light of this case, we recommend that patients with HS should be checked for the presence of Demodex spp., and if it is detected, an appropriate treatment should be applied. To our knowledge, this is the first case report presenting the relationship between HS and Demodex infestation.


Dermatology Journal and/or Publisher

Journal Name: Turkiye parazitolojii dergisi
Journal Abbreviation: Turkiye Parazitol Derg
Journal Date Published:


National Center for Biotechnology Information

PMID: 29780007
Article Source: http://www.ncbi.nlm.nih.gov/pubmed/29780007
Lasted Revision: 2018-05-21


Abstract Source: National Center for Biotechnology Information, U.S. National Library of Medicine Abstract Query for Hidradenitis suppurativa (HS).


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