Hidradenitis suppurativa Debilitating and challenging to treat

VICTORIA HARRIS MB BS, LLB ANDREW LEE MB BS, MMed SHIVAM KAPILA MB BS, BSc(Med), MS ALAN COOPER OAM, BSc, MB BS, FACD

Hidradenitis suppurativa (HS) is a debilitating chronic skin disease. It is characterised by painful nodules that may progress to abscesses and in severe cases can lead to sinus tract formation, fibrotic scarring, dermal contractures and skin induration. HS causes significant morbidity because of its painful remitting and relapsing course. The pathogenesis is not completely understood but primarily involves occlusion of terminal hair follicles and subsequent hyperkeratinisation and inflammation.1\ There are a number of theories to explain these histological changes, which implicate factors such as obesity, tobacco smoking, genetics, inflammation and hormonal variation. There is currently no single effective therapy for this condition, and management often involves a combination of medical and surgical options.

Hidradenitis suppurativa is a debilitating chronic skin disease of intertriginous areas, which may be misdiagnosed as boils or ingrown hairs in the early stages. Treatment often requires a combination of lifestyle modifications, medications and laser or surgical interventions.

PDFhttp://medicinetoday.com.au/

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