Effectiveness of 5-aminolevulinic acid photodynamic therapy in the treatment of hidradenitis suppurativa: a report of 5 cases

Hidradenitis suppurativa Research


Author(s): Andino Navarrete R, Hasson Nisis A, Parra Cares J

Hidradenitis suppurativa has been described as a chronic, recurrent, and disabling inflammatory disease involving the entire hair follicle. Several treatments, including photodynamic therapy, have been used, but the results have been inconsistent and recurrence is high. In this prospective study, we evaluated disease severity, quality of life, and treatment tolerance in 5 patients with moderate to severe hidradenitis suppurativa treated with photodynamic therapy using 5-aminolevulinic acid and a 635-nm light source. Treatment effectiveness was evaluated using the Sartorius severity score, the Dermatology Life Quality Index, and a visual analog scale for pain and disease activity. Significant improvements were observed with all 3 instruments and the effects remained visible at 8 weeks. Our results suggest that photodynamic therapy with 5-aminolevulinic acid and a light wavelength of 635 nm could reduce disease severity and improve quality of life in patients with difficult-to-treat hidradenitis suppurativa.


Dermatology Journal and/or Publisher

Journal Name: Actas dermo-sifiliograficas
Journal Abbreviation: Actas Dermosifiliogr
Journal Date Published: 2014-07-01


National Center for Biotechnology Information

PMID: 24472519
Article Source: http://www.ncbi.nlm.nih.gov/pubmed/24472519
Lasted Revision: 2014-07-01


Abstract Source: National Center for Biotechnology Information, U.S. National Library of Medicine Abstract Query for Hidradenitis suppurativa (HS).


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