Author(s): Danby FW
PURPOSE OF REVIEW: This review is intended to provide the background aetiopathogenetic framework upon which management of this disorder can be based, particularly with relation to new concepts of the pathogenesis of the disorder. The emphasis is on the prevention of the disorder’s full expression by addressing the metabolic changes that drive the underlying structural damage and the immune system’s subsequent reaction to this damage.
RECENT FINDINGS: The mechanism by which dietary factors impact on this disease are elucidated, the anatomic defect suspected to be responsible for the disorder is introduced, and an updated flow sheet describing and linking the clinicopathological changes recently described are provided.
SUMMARY: Recent work in the understanding of the induction and evolution of the lesions provides a background upon which the preventive regimen and both the medical and surgical approaches can be effectively based.
Dermatology Journal and/or Publisher
Journal Name: Current opinion in pediatrics
Journal Abbreviation: Curr. Opin. Pediatr.
Journal Date Published: 2015-07-13
National Center for Biotechnology Information
Article Source: http://www.ncbi.nlm.nih.gov/pubmed/26087422
Lasted Revision: 2015-07-13
Abstract Source: National Center for Biotechnology Information, U.S. National Library of Medicine Abstract Query for Hidradenitis suppurativa (HS).