Adalimumab is an antibody that binds to TNF-alpha and interferes with its interaction with cell surface receptors. This product is marketed as Humira for the treatment of rheumatoid arthritis and Crohn’s disease.According to information submitted to the FDA, no adverse effects were noted in the offspring of monkeys treated with up to 100 mg/kg each week. This dose is at least 266 times the recommended human dose based on plasma concentrations.When a comparable antibody to mouse TNF alpha was administered to pregnant mice, there were no adverse effects on fetal survival or morphologic development (8). There were no adverse effects on immune function in the offspring except an inconsistent decrease in splenic cell expansion in females but not males (9). This observation may not be clinically important.Dermatology HUMIRA Pregnancy Treatment
Adalimumab During Pregnancy: Side Effects and Risks
Lymphedematous verrucous changes simulating squamous cell carcinoma in long-standing hidradenitis suppurativa, PUBMED Research, Research, Dermatology, 0
Journal: Int. J. Dermatol. 2013 Jul;52(7):808-12 Author(s): Chu EY, Kovarik CL, Lee RA BACKGROUND: Hidradenitis suppurativa (HS) is a...
- , PUBMED Research, Research, Dermatology, 0
Journal: Arch Dermatol 1976 Aug;112(8):1132-4 Author(s): McDonald RM, Reed WB A new syndrome, consisting of natal or defective teeth,...
Promising long-term outcomes of the reused skin-graft technique for chronic gluteal hidradenitis suppurativa, PUBMED Research, Research, Dermatology, 0
Journal: J Plast Reconstr Aesthet Surg 2015 Sep;68(9):1268-75 Author(s): Maeda T, Kimura C, Murao N, Takahashi K BACKGROUND: The...
Hidradenitis suppurativa (HS) Non-Profit (501c3) 2017 Registration
We are currently fundraising for the Non-Profit (501c3) registration of HSAWARENESS.ORG and our growing organization NGO at large. We cannot realize this next and essential step for our critical work without you.
“I WILL NOT HIDE” Hidradenitis suppurativa (HS) Patient Stories Book Series
The “I WILL NOT HIDE” Hidradenitis Suppurativa book series is now available. These patient story volumes tell the stories of Hidradenitis Suppurativa (HS) patients in vivid and personal narrative. Told by HS patients themselves.
HSAWARENESS EMAIL UPDATES
Join our mailing list to learn more about the measurable results being made for the patients of rare and orphan disease communities.