Adalimumab is an antibody that binds to TNF-alpha and interferes with its interaction with cell surface receptors. This product is marketed as Humira for the treatment of rheumatoid arthritis and Crohn’s disease.According to information submitted to the FDA, no adverse effects were noted in the offspring of monkeys treated with up to 100 mg/kg each week. This dose is at least 266 times the recommended human dose based on plasma concentrations.When a comparable antibody to mouse TNF alpha was administered to pregnant mice, there were no adverse effects on fetal survival or morphologic development (8). There were no adverse effects on immune function in the offspring except an inconsistent decrease in splenic cell expansion in females but not males (9). This observation may not be clinically important.Dermatology HUMIRA Pregnancy Treatment
Adalimumab During Pregnancy: Side Effects and Risks
Secondary Comedones in a Case of Acne Conglobata Correlate with Double-ended Pseudocomedones in Hidradenitis Suppurativa, PUBMED Research, Research, 0
Author(s): Lacarrubba F, Dall’Oglio F, Musumeci ML, Nasca MR, Micali G Dermatology Journal and/or Publisher Journal Name: Acta dermato-venereologica...
- , PUBMED Research, Research, 0
Author(s): Dabernig J, Sorensen K, Shaw-Dunn J, Hart AM The development of microsurgery has most recently been focused upon...
Managing patients with delusional infestations in an integrated psychodermatology clinic is much more cost-effective than a general dermatology or primary care setting, PUBMED Research, Research, Mental Health, Psychodermatology, Psychology, 0
Author(s): Altaf K, Mohandas P, Marshall C, Taylor R, Bewley A Dermatology Journal and/or Publisher Journal Name: The British...
- , Topics, 0
La enfermedad es más frecuente en las mujeres y se conoce como acné inversa. El Dr Por ejemplo, ingle,...
Biomarkers and Personalized Medicine: Current Status and Further Perspectives with Special Focus on Dermatology, Research, Dermatology, 0
Biomarkers and Personalized Medicine: Current Status and Further Perspectives with Special Focus on Dermatology
Higher Risk of Care for Hidradenitis Suppurativa in African American and Non-Hispanic Patients in the United States, PUBMED Research, Research, 0
Author(s): Udechukwu NS, Fleischer AB Hidradenitis suppurativa (HS) is a chronic cutaneous inflammatory disease. Few reports have been published...
- , PUBMED Research, Research, 0
Author(s): Güngör S, Yüksel T, Topal I Dermatology Journal and/or Publisher Journal Name: Indian journal of dermatology, venereology and...
“I WILL NOT HIDE” Hidradenitis suppurativa (HS) Patient Stories Book Series
The “I WILL NOT HIDE” Hidradenitis Suppurativa book series is now available. These patient story volumes tell the stories of Hidradenitis Suppurativa (HS) patients in vivid and personal narrative. Told by HS patients themselves.
HSAWARENESS EMAIL UPDATES
Join our mailing list to learn more about the measurable results being made for the patients of rare and orphan disease communities.
The Latest PUBMED Medical ResearchView All HS Research
- Acne inversa/hidradenitis suppurativa: An update November 20, 2017
- Correction to: Pain, Psychological Comorbidities, Disability, and Impaired Quality of Life in Hidradenitis Suppurativa November 18, 2017
- Response to “IL-36 in hidradenitis suppurativa: Evidence for a distinctive pro-inflammatory role and a key factor in the development of an inflammatory loop” November 18, 2017
- Hidradenitis suppurativa-like lesions associated with pharmacologic inhibition of gamma-secretase November 11, 2017
- Longitudinal observational study of hidradenitis suppurativa: impact of surgical intervention with adjunctive biologic therapy November 11, 2017