Acne inversa (Hidradenitis suppurativa): A review with a focus on pathogenesis and treatment

Hidradenitis suppurativa Research


Author(s): Wollina U, Koch A, Heinig B, Kittner T, Nowak A

Acne inversa (AI) is a disabilitating chronic inflammatory disease with major negative impact on quality of life and significant co-morbidities. This is an important link to insights into immune dysfunction, which stimulated therapeutic approaches like tumor necrosis-α inhibitor therapy. This new off-label drug treatment is particularly beneficial when used in combination with wide excision of inflamed skin and subcutaneous tissue. Retinoids have been reported to be helpful in secondary prevention. The standard of therapy in advanced cases is surgery with wide excisions and healing by secondary intention. This treatment results in significant reduction of complaints and achieves satisfactory body contouring.


Dermatology Journal and/or Publisher

Journal Name: Indian dermatology online journal
Journal Abbreviation: Indian Dermatol Online J
Journal Date Published: 2013-02-26


National Center for Biotechnology Information

PMID: 23439959
Article Source: http://www.ncbi.nlm.nih.gov/pubmed/23439959
Lasted Revision: 2017-02-20


Abstract Source: National Center for Biotechnology Information, U.S. National Library of Medicine Abstract Query for Hidradenitis suppurativa (HS).


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