Accutane (Isotretinoin) requires caution – PASH (PG, acne and hidradenitis suppurativa) mentioned

accutane for hidradenitis suppurativa


“While dermatologists are fairly comfortable overlapping isotretinoin and prednisone, she added, there’s little data about combining isotretinoin with prednisone alternatives including oral antibiotics, or about isotretinoin alternatives such as TNF inhibitors, cyclosporine, dapsone and levamisole.”

“AF-associated disorders such as SAPHO (synovitis, acne, pustulosis, hyperostosis and osteitis), PAPA syndrome (pyogenic arthritis, pyoderma gangrenosum/PG and acne) and PASH (PG, acne and hidradenitis suppurativa) are extremely rare, said Dr. Zaenglein. “Understanding and considering these syndromes will be useful in the future as we try to understand more about why some patients have acne fulminans flares, while others do not.”

Quoting excerpts from: Isotretinoin requires caution in acne fulminans


 

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