Absence of efficacy of oral isotretinoin in hidradenitis suppurativa: a retrospective study based on patients’ outcome assessment

Hidradenitis suppurativa Research


Author(s): Soria A, Canoui-Poitrine F, Wolkenstein P, Poli F, Gabison G, Pouget F, Viallette C, Revuz J

BACKGROUND: In analogy to acne, oral isotretinoin has been considered in the treatment of hidradenitis suppurativa (HS).

OBJECTIVES: To assess the efficacy of oral isotretinoin according to patients.

METHODS: From 1999 to 2006, 358 consecutive HS patients were interviewed and examined. A standardized record of the data was performed for each patient during the first consultation. Patients were questioned regarding the effect of previous treatment with oral isotretinoin: patients had to grade the effect as either ‘improved’, ‘no effect’ or ‘worse’.

RESULTS: Fourteen patients (16.1%) declared an improvement, 67 patients (77%) no effect and 6 patients (6.9%) worsening of HS.

CONCLUSION: According to our patients, oral isotretinoin is not effective in the treatment of HS.


Dermatology Journal and/or Publisher

Journal Name: Dermatology (Basel, Switzerland)
Journal Abbreviation: Dermatology (Basel)
Journal Date Published: 2009-01-29


National Center for Biotechnology Information

PMID: 19060466
Article Source: http://www.ncbi.nlm.nih.gov/pubmed/19060466
Lasted Revision: 2015-11-19


Abstract Source: National Center for Biotechnology Information, U.S. National Library of Medicine Abstract Query for Hidradenitis suppurativa (HS).


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