Author(s): Adiga A, Pixley J
Hidradenitis suppurativa (HS) is a chronic, inflammatory follicular skin disease with recurrent skin nodules, sinus tracts, and scarring. We observed a case of HS associated with relapsing polyarthritis. On presentation the patient had a flare of polyarthritis with an increase in the number and size of pustular nodules. He has had similar episodes 1 to 2 times yearly subsiding with antibiotic treatment. Radiographs revealed erosions and demineralization. Symptoms improved following institution of anti-inflammatory and antibiotic therapy. HS is associated with several inflammatory conditions, and dysregulation in innate immunity may play an important role in etiopathogenesis. Spondyloarthritis/sacroiliitis is the most common joint manifestation in HS and mechanism(s) underlying arthropathy is unknown. Treatment of arthritis in HS is anecdotal.
Dermatology Journal and/or Publisher
Journal Name: Journal of investigative medicine high impact case reports
Journal Abbreviation: J Investig Med High Impact Case Rep
Journal Date Published: 2016-11-29
National Center for Biotechnology Information
Article Source: http://www.ncbi.nlm.nih.gov/pubmed/27896279
Lasted Revision: 2017-08-16
Abstract Source: National Center for Biotechnology Information, U.S. National Library of Medicine Abstract Query for Hidradenitis suppurativa (HS).